This study investigated the perceived impact of entrepreneurship education on career development among undergraduates in south-south universities in Nigeria. To guide the study four research questions were generated and one hypothesis formulated, which was tested at 0.05 level of significance. The study employed an expost facto research design. The population of the study consists of all undergraduates in south-south universities in Nigeria. Sample size consists of 150 students who were randomly drawn and who had undertaken entrepreneurship studies. The main instrument for the study was a questionnaire titled Entrepreneurship Education and career development scale (EECDS). Data was analyzed using descriptive statistics for the research questions and t-test for hypothesis. The result showed that there are inadequate facilities and effective teaching and learning of entrepreneurship education in Nigerian universities. Moreover, it was also found that the students were of the view that entrepreneurship education will provide training that would make undergraduates creative and innovative if the programme is properly implemented.