This research aimed to analyze the Latent Group Profile, hereafter (LPA) of good teacher characteristics' in the 21st century in the Northeastern region of Thailand. The samples were 4 groups, viz; 10 expert teachers for interviewing on the draft of the variable to develop the indicators; 12 teachers who won Guru Awards from Teachers Council for in-depth interviewing and use the data to adjust the variable to confirm good teacher characteristics' in the 21st century in a real situation. 1,103 primary school teachers in the Northeastern region were random from 11 provinces and were selected by applying multi-stage sampling technique and employed them for second-order confirmatory factor analysis. The research instrument was a set of 71 items questionnaire focusing on the good teacher characteristics' in the 21st century. The reliability of the questionnaire was at 0.933 and the discrepancy was between 0.264-0.696. The research findings revealed that, the LPA had 3 models, and the numbers of the groups in each model were 2, 3 and 4, respectively. When considering the probability that the classification was the most accurate (E_k), it was the model with 2 groups (likelihood = -7138.381, AIC = 14344.763, BIC = 14514.960, ABIC = 14406.967, E_k = 0.954). The proportion of the teachers in the LPA group 1 were 483 teachers, who were being a good role model for the learners (43.79%) and the LPA group 2 were 620 teachers, who believed in good values (56.21%).