Purpose: In this paper, we explore the strategic role of Multi-stakeholder processes (MSP) in agricultural innovations and how it has impacted livelihood assets' (LAs) capital dynamics of stakeholders in platforms in West Africa. Design/Methodology/Approach: We demonstrate how LA capitals and socio-economic dynamics induced by MSP can enhance cassava production efficiency but also create opportunities and challenges that influence platform dynamics and impacts. We use a multistage sampling procedure and sustainable livelihood model (e.g. stochastic frontier functions and Tobit regression) to analyse LA capital dynamics of the stakeholders. Findings: We showed that the LA of the MSP participants (0.72) was found to be significantly higher (X[superscript 2] = 3.732, p < 0.10) than that of the non-participants (0.45). The results further revealed a remarkable increase from 0 to 0.77 and from 0.33 to 0.82 for human capital and social capital, respectively, as stakeholders participate in MSPs' activities. Practical implications: We recommend the institutionalization of MSP in the Agricultural Research for Development (AR4D) with more extension follow-up services so as to adequately and appropriately unleash the potentials in social capital networks that enable the development, effective dissemination and adoption of agricultural innovations. Theoretical implications: This study suggests that soft-transfer of technologies seems to dominate at MSP inception. But at maturity, the results of the struggle between researchers and farmers would lead to co-reaction and community-based research. Consequently, the knowledge and power dynamics that take place within the MSP should be considered the centre of co-construction and platform dynamics. Originality/Values: The study provided a practical experience on how MSP can be institutionalized in the AR4D programmes to support agricultural innovation systems and foster pro-poor growth and livelihoods.