E-learning is emerging as the new phenomenon of modern education. Universities are adopting e-learning as a strategy for the improving the teaching/learning process. The primary question addressed in this paper is related to the factors influencing the adoption of e-learning. An integrated model was used to explore the factors influencing students' satisfaction with e-learning in Jordan. The model adopted five variables from the technology acceptance model, Delone and McLean model and the social cognitive theory to predict students' satisfaction with e-learning. A sample of 386 students was utilized and an instrument with 30 items was used. Results indicated that perceived ease of use, perceived usefulness, system quality, information quality, and computer self-efficacy are major factors influencing students' satisfaction. The coefficient of determination estimated to be 0.498, and yielded a full support of all proposed hypotheses. Conclusions and future work are reported at the end of this study.