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ERIC Number: EJ1166036
Record Type: Journal
Publication Date: 2018-Jan
Pages: 14
Abstractor: As Provided
ISSN: ISSN-0162-3257
Association between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity among Children with Autism Spectrum Disorder
Kerin, Tara; Volk, Heather; Li, Weiyan; Lurmann, Fred; Eckel, Sandrah; McConnell, Rob; Hertz-Picciotto, Irva
Journal of Autism and Developmental Disorders, v48 n1 p137-150 Jan 2018
Prenatal exposure to air pollution has been associated with autism spectrum disorder (ASD) risk but no study has examined associations with ASD severity or functioning. Cognitive ability, adaptive functioning, and ASD severity were assessed in 327 children with ASD from the Childhood Autism Risks from Genetics and the Environment study using the Mullen Scales of Early Learning (MSEL), the Vineland Adaptive Behavior Scales (VABS), and the Autism Diagnostic Observation Schedule calibrated severity score. Estimates of nitrogen dioxide (NO[subscript 2]), particulate matter (PM[subscript 2.5] and PM[subscript 10]), ozone, and near-roadway air pollution were assigned to each trimester of pregnancy and first year of life. Increasing prenatal and first year NO[subscript 2] exposures were associated with decreased MSEL and VABS scores. Increasing PM[subscript 10] exposure in the third trimester was paradoxically associated with improved performance on the VABS. ASD severity was not associated with air pollution exposure.
Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: National Institute of Environmental Health Sciences (NIEHS) (NIH); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (NIH); National Institute of Mental Health (DHHS/NIH); US Environmental Protection Agency
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Mullen Scales of Early Learning; Vineland Adaptive Behavior Scales; Autism Diagnostic Observation Schedule
Grant or Contract Numbers: ES013678; ES019002; ES11269; ES015359; HD079125; MH073124; 829388; 833292