The field of positive behavior support (PBS) has expanded and evolved significantly since the first issue of "Journal of Positive Behavior Interventions" ("JPBI") was published. To ascertain how evolution of the field was reflected in the research, we examined trends in empirical studies published in "JPBI" since its inception. We coded 217 articles published between 1999 and 2016 that included data-based assessment or data-based intervention practices for key variables pertinent to potential trends in PBS. Analyses revealed increases across the publication period in studies that (a) included participants at risk for behavioral difficulties, (b) implemented interventions in general education settings, (c) utilized clinicians/experimenters as intervention agents, and (d) focused on adult skills as the intervention target. Findings are discussed in the context of the expansion of school-wide positive behavior interventions and support.