The combination of Qualitative Comparative Analysis (QCA) with process tracing, which we call set-theoretic multimethod research (MMR), is steadily becoming more popular in empirical research. Despite the fact that both methods have an elected affinity based on set theory, it is not obvious how a within-case method operating in a single case and a cross-case method operating on a population of cases are compatible and can be combined in empirical research. There is a need to reflect on whether and how set-theoretic MMR is internally coherent and how QCA and process tracing can be integrated in causal analysis. We develop a unifying foundation for causal analysis in set-theoretic MMR that highlights the roles and interplay of QCA and process tracing. We argue that causal inference via counterfactuals on the level of single cases integrates QCA and process tracing and assigns proper and equally valuable roles to both methods.