This Communication summarizes one of the invited papers to the Select 2016 BCCE Presentations ACS CHED Committee on Computers in Chemical Education online ConfChem held from October 30 to November 22, 2016. The supplemental instruction (SI) model has come a long way from being a peer-assisted study sessions geared toward improving student retention and success. Students now have 24/7 access to handouts, professional tutoring by an SI leader, and group collaboration outlets; several of these services are offered via social media sites. How well these outlets are incorporated into the classroom is now a key component of what makes an SI session successful. With the advent of these innovations, the limits to what the SI leader can provide to their students are far fewer. Some of these innovations include (but are not limited to): video lectures, practice exams, and promotion of group collaboration among students. Through the use of platforms including Facebook, Twitter, Piapp, and Slack, the SI session can be held almost exclusively online and provide just as much if not more benefit to the students involved.