The Manoomin ''wild rice'' Science Camp program, a partnership between the University of Minnesota, the Fond du Lac Tribal and Community College, and the Fond du Lac Band of Lake Superior Chippewa is an example of how a community-based participatory research project can become the catalyst for STEM learning for an entire community, providing effective learning opportunities for grades 5-12 and undergraduate students, elementary and secondary school teachers, and scientists from the reservation, tribal college, and university. Focusing the research on a resource (wild rice) that has important economic, cultural and spiritual meaning for a community, we promote place-based education and support the development of strong science/teacher/community partnerships. Key components of this approach are the Circle of Learning, a conceptual framework that emphasizes trust- and relationship-building between researchers, teachers, students, and American Indian community members, and the Seven Elements of STEM Learning, a pedagogical framework derived from an extensive review of the literature on American Indian education that focuses on a holistic approach to learning that emphasizes the whole student.