In this article, we trace the development of the Campbell Collaboration and its renewed efforts to build a world library of accurate, synthesized evidence to inform policy and practice and improve human well-being worldwide. Campbell systematic reviews and related evidence synthesis products provide unbiased summaries of entire bodies of empirical evidence, making them uniquely useful sources of information for policy and practice. With recent changes in organizational structure and new leadership, the Campbell Collaboration is poised to dramatically increase the production, dissemination, and use of rigorous syntheses of research on social, economic, and behavioral interventions. Campbell provides opportunities for social work scholars, practitioners, and consumers to contribute to knowledge about the processes and outcomes of social, behavioral, and economic interventions.