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ERIC Number: EJ1159468
Record Type: Journal
Publication Date: 2017-Oct
Pages: 4
Abstractor: As Provided
ISSN: ISSN-0021-9584
Using Myoglobin Denaturation to Help Biochemistry Students Understand Protein Structure
Miao, Yilan; Thomas, Courtney L.
Journal of Chemical Education, v94 n10 p1498-1501 Oct 2017
Analyzing and understanding data directly from primary literature can be a daunting task for undergraduates. However, if information is put into context, students will be more successful when developing data analysis skills. A classroom activity is presented using protein denaturation to help undergraduate biochemistry students examine myoglobin structure. Student learning goals are to understand relationships involving molar absorption coefficients and light absorbance, quantum yield and fluorescence, guanidine hydrochloride and protein folding, as well as protein folding and spectral properties of aromatic amino acids. This activity was performed by 56 students over three years. Results show statistically significant gains in student learning and student reported increased understanding.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A