NotesFAQContact Us
Search Tips
Peer reviewed Peer reviewed
Direct linkDirect link
ERIC Number: EJ1159451
Record Type: Journal
Publication Date: 2017-Oct
Pages: 6
Abstractor: As Provided
ISSN: ISSN-0021-9584
Complete LabVIEW-Controlled HPLC Lab: An Advanced Undergraduate Experience
Beussman, Douglas J.; Walters, John P.
Journal of Chemical Education, v94 n10 p1527-1532 Oct 2017
Virtually all modern chemical instrumentation is controlled by computers. While software packages are continually becoming easier to use, allowing for more researchers to utilize more complex instruments, conveying some level of understanding as to how computers and instruments communicate is still an important part of the undergraduate curriculum. Understanding how digital and analog signals are used to allow the smooth operation of an instrument allows the user to better understand the possible sources or problems when instruments stop working optimally. The experiment presented here allows students to investigate the communication between the computer and a high-performance liquid chromatography (HPLC) system by allowing them to construct a LabVIEW-based control program. Student understanding of instrument control is reinforced by having them control pump speed, detector zeroing, and a solvent recycling valve while also monitoring the injection port status and the detector output. Students gain an understanding of the HPLC process by incorporating all of the instrument tasks into their control software and then use their system to analyze a mixture of five small organic molecules, thereby gaining insight into the chemical concepts underlying HPLC separations.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Minnesota
Grant or Contract Numbers: N/A