In this study, we manipulated mastery criterion form (rolling or block) and stringency (across 6 or 12 trials) and measured the emergence of derived relations. College students learned neuroanatomy equivalence classes and experienced one of two rolling mastery criteria (6 or 12 consecutive correct responses) or a block mastery criterion (12 trials in a block) during training. The study found that block and rolling mastery criteria produced similar outcomes. Effectiveness was hampered when the criterion was less stringent.