Accessibility and findability of digitized archival resources can be a challenge, particularly for students or researchers not familiar with archival formats and digital interfaces, which adhere to different descriptive standards than more widely familiar library resources. Numerous aggregate archival collection databases exist, which provide a means by which to search across collections from many institutions. However, no single database is comprehensive, and many also lack robust capabilities for subject-based browsing to target science, technology, engineering, and mathematics (STEM) collections. This webliography is intended as a guide to an array of digitized archival collections documenting progressive work in STEM disciplines over time. It is selective in scope, with the intent to highlight a strong set of collections that preserve the work and lives of prominent STEM and allied researchers from diverse fields, including the natural and physical sciences, technology, computer science, engineering, and medicine. The selected resources in this webliography are intended as a starting point by which librarians, archivists, educators, and students may discover digitized archival primary sources related to STEM and allied disciplines, which may be creatively used as tools to inform instruction, teaching, research, library collection development, marketing, and reference services. The resources demonstrate a wide-ranging selection of noteworthy, historically significant STEM-focused archival primary source collections currently digitized and publicly accessible.