The 21st century nurse is a forward-thinking individual who is expected to deliver holistic nursing care. Multigenerational learners are seeking degrees and the new Net generation learner will reflect the majority of the workforce. Thus, the integration of a multilevel interactive classroom is instrumental in facilitating the student's knowledge acquisition phase. Prelicensure nursing students are expected to know and understand the multifaceted topic of end-of-life (EOL) care. Gillan, van der Riet, and Jeong (2014) reported that nursing students are not adequately prepared to provide care for a patient at the end of life. The online module using Raptivity and iSpring is part of an EOL study to evaluate the nursing students' attitudes toward providing care at the end of life. The module was designed for accelerated bachelor of science nursing students to integrate the key concepts related to caring for a patient and family at the end of life. This article will describe the development and implementation of an interactive end of life online module for second-semester students at a school of nursing in a 4-year university in Southern Florida. In addition, the article will include the lessons learned from integrating the innovative technological applications and the benefits to educators.