Implementation of universal design for learning (UDL) in undergraduate special education programs offers a valuable foundation for training preservice teachers to educate K-12 students in rural schools. In this article, we provide an overview of UDL and the integration of multiple means of representation, engagement, and expression in assessment, classroom management, and instructional planning courses. We share examples of faculty modeling, guided instruction, and preservice teacher application of UDL components with case studies and K-12 students in practicum experiences. We discuss challenges, implications, and next steps for integrating UDL in rural university and K-12 classrooms to meet the needs of diverse learners.