Barack Obama's "My Brother's Keeper" is designed to narrow persistent gaps that boys and young men of color confront often and to help all young people achieve their potential in college and career. An important part of this initiative is comprehensive mentoring that supports students in schools and in communities. Because ethnic-minority students have extremely low graduation rates in high school and college, an essential question is addressed: Can "My Brother's Keeper" and similar initiatives with a mentoring component be effective in helping minority students to achieve success in elementary and secondary schools and in college?