This article outlines one way in which less research-intensive universities can contribute to entrepreneurship by examining the achievements of several Knowledge Transfer Partnerships (KTPs) in the University of Gloucestershire. The article adopts a qualitative case study approach: four case studies of KTPs at, respectively, Beacons Business Interiors, Dowty Propellers, Energist UK and Muddy Boots Software (all of which have operating bases within 40 miles of the University) are researched and analysed. The findings reveal that these four KTPs delivered various benefits for the companies, the University and the staff directly involved in the projects, and more generally that the KTPs successfully met their initial aims. The authors identify a number of challenges involved in maximizinig the benefits of KTP activity in the University and suggest how KTPs can actively foster the development of an entrepreneurial university. This article is an accessible review of KTP initiatives in the University of Gloucestershire and as such will interest academics and business practitioners who are looking to develop university--industry partnerships. It also offers reflections on how a programme of KTPs can advance entrepreneurial development and support Growth Hub initiatives.