The study compares self-concept, locus of control, and goal orientation characteristics of male and female Mexican high school high-achieving students. Three scales were administered to 220 students; 106 (49%) were males and 114 (51%) females. By means of a discriminant analysis, both groups were compared in relation to the variables such as social self-concept, academic self-concept, achievement motivation toward study, and attributions regarding academic success or failure. It was found that female students have a better academic self-concept and a higher achievement motivation than males. Findings are consistent with previous studies in Mexico that provide evidence of females having greater emotional resources associated with school success.