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ERIC Number: EJ1145974
Record Type: Journal
Publication Date: 2017-Jun
Pages: 6
Abstractor: As Provided
ISSN: ISSN-0021-9584
Lipase-Mediated Kinetic Resolution: An Introductory Approach to Practical Biocatalysis
Bandeira, Pamela T.; Thomas, Juliana C.; de Oliveira, Alfredo R. M.; Piovan, Leandro
Journal of Chemical Education, v94 n6 p800-805 Jun 2017
An experimental protocol that provides an excellent way to discuss concepts at the crossroads of organic chemistry and biochemistry employing biocatalysis is presented. By evaluating several reaction parameters (enzyme source, organic solvent, and acyl donor), it was possible to conduct an enzymatic kinetic resolution experiment using 1-phenylethanol as a model compound. Students were then challenged to revisit and explore a variety of basic principles already addressed in previous organic chemistry or biochemistry courses to stimulate interdisciplinary research.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive; Guides - Classroom - Teacher
Education Level: Higher Education; Postsecondary Education
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A