Introduction: This study aims to (a) construct a typology of how individuals acquire cancer information, and (b) examine whether these types differ regarding socio-demographics and cancer-related knowledge, attitudes and behaviour. Method: A standardized, cross-sectional survey among cancer diagnosed and non-diagnosed individuals in Flanders, Belgium (N= 2008) was conducted. Analysis: A two-step cluster algorithm based on mediated and interpersonal cancer information seeking and scanning, and on cancer information avoiding behaviour was used. Bivariate differences between those clusters were calculated using the chi-squared measure and one-way ANOVAs with Tukey post-hoc tests. Results: Three meaningful clusters of cancer information acquisition were identified--selective users, full users and low users. Significant differences between those clusters were found in terms of socio-demographics, cancer knowledge, health perception, cancer risk perception, fear of cancer, Internet use and lifestyle behaviour. Conclusion: These results indicate that different cancer information acquisition typologies exist and that they have different associates. This highlights the relevance of looking at individual levels of cancer information acquisition types. As some individuals prefer to have more information on cancer and appear to be more open to it than others, tailoring cancer communication to the individual's information acquisition style might be a path worth exploring.