The purpose of this study is to examine the influence of organizational learning on employee's innovative behavior, and further proposed the mediation effect of work engagement between the relationship of organizational learning and employee's innovative behavior. The study targets on executives and their subordinates by paired samples within the Southern Taiwan Science Park and a total of 21 useful firms collected, including 54 managers and 511 employees, and to evaluate research model by using hierarchical linear modeling (HLM). The empirical results indicated that work engagement fully mediated the relationship between organizational learning and employee's innovative behavior, that is, executives with organizational learning can strengthen the work engagement of employees, thereby affecting employee's innovation behavior. Besides, we further found that work engagement also plays a full mediating role among organizational learning and employee's innovative ideas generation, advocacy, and implementation respectively. This paper suggests managers should take advantage of their learning culture to enhance their employees' work engagement and then this is also beneficial for the generation of innovative behavior of employees.