This article focuses on the multicultural nature of distance learners. To note, the heightened demand for higher education on a global scale, as well as rapid advancements in telecommunication technologies, have rendered online distance education as having potential for worldwide reach online schools in many countries. Because of this, online educators should design instruction in such a way that people from different cultural backgrounds effectively learn from it. Indeed, instructors and instructional designers, particularly those working in online learning environments, should develop the necessary skills so they are able to deliver "culturally sensitive and culturally appropriate and robust instruction." The article explores the relevant concepts such as the cultural dimension of distance learning, instructional design that is culturally appropriate, learning as impacted by culture, as well as the need for multicultural competency training for distance school instructors. The article also explores the barriers to effectiveness in delivery of culturally appropriate instruction in the context of distance learning. The theoretical foundation for the article is Freire's critical pedagogy.