Corporate entrepreneurship is a critical area of curricula for computer science and information systems students. Few institutions of computer science and information systems have entrepreneurship in the curricula however. This paper presents entrepreneurial health informatics as a course in a concentration of Technology Entrepreneurship at a leading institution of technology. In the concentration, and in the course, students are learning to be business entrepreneurs in interdisciplinary fields, such as health. This paper can be beneficial to educators in schools of computer science and information systems desiring to enrich offerings to be contemporary with the demands of industry.