The purpose of the study was to assess adolescents' participation in various socio-digital activities by using a self-report questionnaire, a social networking questionnaire, and interviews. The participants (n = 253) were grade 6-9 students from a multicultural lower-secondary school in Finland. Three profiles of socio-digital participation were identified: friendship oriented "basic participators" (n = 161), "gaming-oriented participators" (n = 61), and "creative participators" (n = 31) intensively engaged in diverse socio-digital practices. The analyses revealed systematic differences in social networking relations as a function of adolescents' social-digital participation profile and gender. The reciprocal values in hanging out, liking, and media multiplexity were highest for creative participators, whereas gaming-oriented participators were less socially active than their peers. The socio-digital expertise of creative participators was socially recognized by a larger group of peers than that of the other groups. The study produces methodological tools suitable for collecting systematic longitudinal data of socio-digital practices of larger groups of adolescents in future.