This perspective piece addresses specifically future lines of inquiry and practice that advance the goals of the agenda through an interdisciplinary approach to leadership studies. Here, the authors explain in-depth the contexts of an interdisciplinary approach to the agenda and address specific challenges therein. In order to provide clarity to this approach, considerations are made with respect to the language, contextual reference points, and tensions regarding measurement of learning. The authors provide impetus for inclusion of particular, salient priorities from the agenda, and address opportunities for practice and future research. Suggestions reveal unique opportunities within an interdisciplinary perspective such as the integration of diverse content and perspectives as well as collaboration across disciplines.