The Standards for Effective Pedagogy and Learning (CREDE, 2014) specify five "transnational universals of teaching" that are especially effective for the rapidly growing population of English language learners in North America. CLASSIC is an evidence-based, CREDE-aligned model of teacher education for classroom educators of English language learners. CLASSIC has utilized with more than 10,000 teachers in 100 school districts, located in eight states, in collaboration with eight different universities. This study examined the impact of the transnational standards of CLASSIC curricula on teachers' observed practices with English language learners as measured by the recently developed "Inventory of Situationally and Culturally Responsive Teaching" (ISCRT). Despite some variability, over 110 participating teachers in 37 U.S. schools demonstrated "statistically significant improvements" in their delivery of effective pedagogy, across a wide range (18 of 22) ISCRT indicators; teachers exhibited "highest levels of growth" in instructional conversations, joint productive activity, and challenging activities.