Our nation's colleges and universities frequently adapt their approach to education in response to the reality of social, economic and environmental challenges. Today the reality is that we are increasingly interconnected on a global scale. This new era of globalization impacts every facet of society, and it offers both an exciting blend of generational change and complex, multifaceted challenges. How shall we educate our students in this new era? What can we expect of our graduates in a global world? The answer to these questions requires our institutions to make significant changes in their approach to educating students and interacting with the communities they serve. This new approach should be shaped by a sense of what it means to be a globally prepared graduate, and should be guided by clear learning outcomes exercised along a sequential pathway of experiences from the first year of college through graduation. These experiences are supported by the use of engaged learning practices that draw students into work that is both personally and socially meaningful, and that includes cross-disciplinary inquiry focused on the goal of addressing big questions in ethical, responsible, and effective ways.