A yoga-based school-wide positive behavior support (SWPBS) may provide a foundation for teaching mindfulness and self-regulation in K-12 schools. Here, the use of yoga as a SWPBS was examined through a review of existing literature and interviews of yoga program facilitators. Yoga was reported to be effective as a pedagogical approach, and found to increase mindfulness, emotional regulation, and positive behaviors of school students. Findings suggest yoga, when provided by culturally sensitive instructors, may be an easy to implement, cost-effective SWPBS in a variety of school settings.