The purpose of this study was to examine the extent that demographic, prior CTE coursework and academic achievement variables predict participation in career academies. Data included information on 17,934 students from 10 comprehensive high schools within one Florida school district in the academic school year of 2012-13. Findings indicated: (a) White students were more likely to participate in career academies compared to racial and ethnic minority students; (b) African American and White students showed no significant difference; (c) females were significantly more likely to participate in career academies; and (d) students from high SES backgrounds and students who performed higher on standardized assessments were more likely to participate in career academies. This study revealed that career academies have similar student profiles compared to CTE programs in general.