This study is a literature review to determine what research says about the relationship between Response to Intervention (RtI) and online student success. Response to intervention is a model used to provide students tools and resources to be successful and engaging in the classroom for academic and behavior challenges (Wright, 2007). Online education has become the hottest idea for obtaining a degree in higher education (Wright, 2007). Adult students of all ages, professions and levels of education seek to step into the next level in completing a degree program. Some adult students may not realize the rigor and demands of an online learning environment and find it more challenging than expected. This literature review will examine what research says about RtI, student learning and student success in online higher education.