The main goal of this paper is to depict the struggle for cultural existence in "Rabbit Proof Fence." It also reflects the cultural conflict represented in the three aboriginal girls' characters which is due to their rejection and resistance for the colonialists' culture. Besides, the paper presents the cognitive analysis of the cultural struggle and resistance in Molly's character, and it tackles the cultural resistance in "Rabbit Proof Fence" from a postcolonial point of view. Additionally, the semiotic dimension, which is based on a socio-cultural basis, is introduced in this paper.