This paper contributes to the ongoing debate about the relationship between the social and the individual as it is enacted in personal learning and the remaking of cultural practices through work. It discusses progress in a two-year study of the work, working lives and learning of 12 individuals: four groups of three employees each. The concept of relational interdependence between individual and social agency is used to understand the progress of their participation, learning and remaking of cultural practices that comprises their work. In identifying and elaborating bases of these interdependencies and their consequences for changes to individuals' cognitive experience and sense of self and the remaking of cultural practices, four linked and overlapping bases for understanding the processes of interdependencies emerge: (i) reflection and review (ii) performance roles; (iii) prospects for dialogue and (iv) how conceptions of rewards and recognition are constructed. In different, but distinct, ways these four bases provide a means to elaborate interdependencies at work, thereby providing a platform to analyse processes of individual learning and the remaking of work practices and concepts throughout working life.