Home visiting programs recognize the importance of promoting women's mental health during and around the time of pregnancy. However, the process of planning and integrating mental health promotion and intervention into the home visiting setting can seem daunting. Using examples and lessons learned from research and practice, the authors provide a framework for facilitating mental health interventions in home visiting. This article discusses conceptual and practical considerations which can assist home visiting programs to facilitate mental health intervention, including intervention content, service delivery context, client perspectives, and community engagement.