Purpose: The purpose of this paper is to present the varied roles played by the University of Lódz (UL) in maintaining and restoring the natural capital of a city as a driver for sustainable city development. The higher education institution can be perceived as visionary, originator and executor of natural capital projects. Design/Methodology/Approach: The paper analyses three cases performed by the Faculty of Biology and Environmental Protection, UL, in the city of Lódz. The activities are based on different scales ranging from city-wide to local, e.g. river and green infrastructure, and which vary in character from policy planning to implementation. Findings: Natural capital projects influence city development on different levels: by the initiation of legal protection, by the implementation of rehabilitation concepts for rivers and by influencing the strategic documents for mid-term and long-term urban development. Originality/Value: The university has the potential for multidisciplinary engagement in the development of urban sustainability. In large-scale projects, academics play a more conceptual role, in capacity building and knowledge transfer, while in local-scale implementations, their role includes innovation, know-how and technology transfer. Moreover, it may act as a reinforcement hub, by safeguarding and strengthening the natural capital of the city.