Teaching large classes poses many challenges to lecturers where massification is a reality in higher education. There are implications for both teaching and effective learning in this context. The need for accountability to learners in education provision served as motivation for a study of large classes in the largest faculty of one university where enrolment figures had recently increased. Semi-structured interviews were conducted with 14 lecturers who teach on average over 500 students in one class. Lecturers reported challenges and experiences related to the higher education environment, resources and support, and teaching and learning. The article provides pointers for supporting lecturers who are teaching large classes based on their identified tensions due to challenges they face. Taking cognisance of lecturers' experiences could guide institutions towards relevant support for academics in the large-class setting and ultimately contribute to accountability and responsible massification of higher education.