Choice of profession is a long process that begins in early childhood and usually lasts for the whole life. That's why it is so important to build a solid vocational guidance school system that will help students to make weighted decisions about their professional future. This system should perform the following functions: engage students in active self-awareness and self-esteem; change student's self-appraisal if it's different from his/her actual capabilities (too high or too low); help students to deepen their knowledge about professions that are interesting to them; teach students to compare their state of health with the demands of a chosen profession; acquaint them with the structure of education; collaborate with their parents. The result of its work is prepared, motivated, active and enterprising young people who know how to take initiative in finding job; adapt acquired professional skills to the needs of the labor market; acquire new skills in difficult situations such as unemployment, new working environment, retraining; be free moving in the new realities of free-market economy; use the art of self-presentation; prepare application documents; use computer and serf on the web. So, the successful choice of future professional life depends on the decision of a gymnasium graduate about his/her further direction of education. And the factor of this successful choice is the knowledge obtained by pupils about themselves, the world of professions, directions of further study in the conditions of lifelong learning program.