This article offers a description and critical evaluation of a novel method for inquiry-based learning (IBL) directed at undergraduate students: a Global Health Hackathon. The hackathon was piloted as part of an "Introduction to Global Health" undergraduate course in order to enable students to gain "and" create knowledge about specific global health-related challenges and, simultaneously, to acquire tangible and transferable skills. We provide a critical evaluation of our practice by drawing on relevant academic literature concerned with IBL, course material to describe the hackathon and its related components and outputs, and student evaluations to reflect on the overall module experience. We conclude by sharing reflections and recommendations of necessary measures required to institutionalize IBL in a more sustainable manner in higher education institutions.