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ERIC Number: EJ1123452
Record Type: Journal
Publication Date: 2016-Dec
Pages: 6
Abstractor: As Provided
ISSN: ISSN-0021-9584
Synthesizing Substituted 2-Amino-2-Chromenes Catalyzed by Tertiaryamine-Functionalized Polyacrylonitrile Fiber for Students to Investigate Multicomponent Reactions and Heterogeneous Catalysis
Xie, Yujia; Liu, Xiaoxing; Tao, Minli
Journal of Chemical Education, v93 n12 p2074-2079 Dec 2016
A multistep experiment for a synthesis laboratory course that incorporates topics in organic synthesis, chemical analysis, and instrumental analysis was developed. Students prepared a tertiaryamine-functionalized polyacrylonitrile fiber (PAN[subscript T]F), and it was subsequently utilized as an immobilized catalyst in a three-component condensation reaction among an aromatic aldehyde, malononitrile, and a-naphthol in ethanol to synthesize substituted 2-amino-2-chromenes in one pot. The fiber catalyst exhibits the advantages of high yield, excellent recyclability and reusability, simple post-treatment, and environmental friendliness. Thus, students were able to apply the concept of green chemistry through catalysis. Moreover, this comprehensive experiment involves a number of unit operations, such as vacuum distillation, filtration, recrystallization, and acid-base titration, which can train the fundamental operation capability of students, and improve their experimental skills.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A