Scholars trained and credentialed in disciplines have a vast array of response options when challenged to engage with others from other disciplinary backgrounds. By considering the ways in which disciplines are like cultures and putting acculturation theory squarely into the domain of interdisciplinary studies, this article takes a new look at these variations. My aim is to undertake a systematic exploration of adjustment processes of the individual disciplinary scholar involved in interdisciplinary work. I discern two fundamental adjustment responses that characterize interdisciplinary engagement: disciplinary maintenance and participation in another discipline. The context for this research is international business (IB) studies, a discipline in which scholars come regularly into contact with research from diverse disciplinary backgrounds. I use a study of scholars from two adjacent subject areas--East Asian studies and economic geography--to explore the many ways scholars make themselves familiar with IB specific repertoire. Consistent with the well-established acculturation modes, my exploration suggests that interdisciplinarity of those in these fields can take on the form of assimilation, integration, separation, and marginalization. I find that scholars' academic background has differential effects on the outcomes of interdisciplinary engagement.