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ERIC Number: EJ1117523
Record Type: Journal
Publication Date: 2016-Nov
Pages: 11
Abstractor: As Provided
ISSN: ISSN-0162-3257
Maternal Exposure to Occupational Asthmagens during Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
Singer, Alison B.; Windham, Gayle C.; Croen, Lisa A.; Daniels, Julie L.; Lee, Brian K.; Qian, Yinge; Schendel, Diana E.; Fallin, M. Daniele; Burstyn, Igor
Journal of Autism and Developmental Disorders, v46 n11 p3458-3468 Nov 2016
Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: National Institute of Environmental Health Sciences (NIEHS) (NIH); Centers for Disease Control and Prevention (DHHS/PHS)
Authoring Institution: N/A
Identifiers - Location: California; Colorado; Georgia; Maryland; North Carolina; Pennsylvania
Identifiers - Assessments and Surveys: Mullen Scales of Early Learning; Autism Diagnostic Observation Schedule
Grant or Contract Numbers: T32ES007018; U10DD000180; U10DD000181; U10DD000182; U10DD000183; U10DD000184; U10DD000498