The urgency of the problem under investigation due to the fact that in most municipal districts with a deficit of financial and other resources are troubled almost all areas of museum activity. The article focused on the study of factor socioeconomic relations of municipal museums. The leading method to the study of this problem is the correlation and regression analysis, allowing to identify the linkages in the form of statistical regularities. On the basis of the study concluded that the indicators of social efficiency of municipal museums play the most prominent role in shaping the performance of museum activities in the municipalities of the Samara region. Article Submissions may be useful in the development of programs for socio-economic development of regions.