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ERIC Number: EJ1117354
Record Type: Journal
Publication Date: 2016-Oct
Pages: 3
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Facilitating Students' Review of the Chemistry of Nitrogen-Containing Heterocyclic Compounds and Their Characterization through Multistep Synthesis of Thieno[2,3-"b"]Pyridine Derivatives
Liu, Hanlin; Zaplishnyy, Vladimir; Mikhaylichenko, Lana
Journal of Chemical Education, v93 n10 p1785-1787 Oct 2016
A multistep synthesis of thieno[2,3-"b"]pyridine derivatives is described that is suitable for the upper-level undergraduate organic laboratory. This experiment exposes students to various hands-on experimental techniques as well as methods of product characterization such as IR and [superscript 1]H NMR spectroscopy, and mass-spectrometry. It also provides an opportunity for students to review important theoretical topics such as nucleophilic substitution, tautomerization, acidity of methylene-active compounds, base-promoted alkylation, and cyclization.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Canada
Grant or Contract Numbers: N/A