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ERIC Number: EJ1115533
Record Type: Journal
Publication Date: 2016
Pages: 16
Abstractor: As Provided
ISSN: EISSN-1306-3065
Laparoscopic Surgical Treatment of Severe Obesity Combined with Gastroesophageal Reflux Disease: A Pilot Randomized Two-Arm Controlled Clinical Study
Ospanov, Oral B.; Orekeshova, Akzhunis M.; Fursov, Roman A.; Yelemesov, Aset A.
International Journal of Environmental and Science Education, v11 n13 p5817-5832 2016
Obesity and gastroesophageal reflux disease (GERD) are serious medical, social, and economic problems of modern society. A pilot randomized two-arm controlled clinical study was conducted to compare laparoscopic plication of the greater gastric curvature combined with Nissen fundoplication (LFN+LGP) versus only Nissen fundoplication (LFN). The study included 114 patients with GERD with a body mass index of 30.0-39.9 kg/m[superscript 2]. The following indices were used to assess efficacy: 24-hour pH-metry with calculation of the DeMeester index, percentage of excess weight loss (EWL%), and patients' quality of life, for which the Bariatric Analysis and Reporting Outcome System with the Moorehead-Ardelt Quality of Life Questionnaire II scoring key was used. Postoperative evaluation of quality of life and the dynamics of key GERD symptoms was conducted with the GERD Health-Related Quality of Life questionnaire. All operations were performed laparoscopically. No significant difference was noted in the anti-reflux function after surgery between the two groups. The bariatric effect (EWL% after 12 months) was better in the LFN+LGP group (45.26 ± 5.80%) than in the LFN group (18.43 ± 4.60%) (p < 0.0001).
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Kazakhstan
Grant or Contract Numbers: N/A