An interdisciplinary approach provides many benefits that warrant the need for its use at technical universities teaching foreign language as an academic discipline. This article reviews recent Russian researches focused on interdisciplinary integration, summarizes advantages and proves overall high efficacy of the interdisciplinary approach to teaching a foreign language for students. When taken as a basis, this approach was found to open up new prospects for implementation of didactic principles of learning at foreign language classes. The article describes the implementation of the principles of interdisciplinary coordination, systematicity and consistency, scientificity, occupational focus, visualization, affordability, strength, consciousness, pro-active behavior, educational training, availability, focus on student's individual character, and intercultural interaction within the framework of the interdisciplinary approach. Incorporation of these principles is demonstrated using training of students of the National Research Nuclear University MEPhI [Moscow Engineering Physics Institute] as an example. At MEPhI, students learn a foreign language during the entire period of their education and study the following credit modules: Introduction into General Technical Foreign Language; General Technical Foreign Language; Occupation-oriented Foreign Language; Foreign Language for Occupation-oriented Communication, Business Communication; Foreign Language for Academic Research; and Communication Foreign Language (in-depth study).