In this study, it's aimed to evaluate the relation between dominant and non-dominant hand perimeters and handgrip strength of basketball, volleyball, badminton and handball athletes. Totally 101 active athletes (49 females, 52 male), of the average age in female 20±1.42 years, in male 21±1.99 years, joined to this study. Height, body weight, BMI (Body Mass Index) and handgrip strength of all the athletes were measured according to international standards. Hand perimeters were measured at a certain standard with digital camera and was calculated with the software developed. The data was analyzed by SPSS 22 programme and Student t test, Pearson Correlation test and One Way Anova was applied. A significance level of p <0.05 was adopted in the analysis. Results of the analysis showed that dominant and non-dominant handgrips of athletes in all disciplines and gender are significantly different and hand and finger perimeters developing different depending on the way they use the ball or racket grip.