The subject of the study in the article is conceptual basis of construction of the target model of interaction between University and region. Hence the topic of the article "the Target model of strategic interaction between the University and the region in the field of education." The objective was to design a target model of this interaction. The methods of study were comparative analysis and instructional design, as well as benchmarking as a methodology of quality control of the interaction. The result was the definition of five main blocks of issues that determine the quality and effectiveness of pre-school, general and additional education at the university. The research results can be used in the design of teacher education in the universities of Russia. This paper therefore concludes that the allocation of basic blocks between the University and the region will allow detailed conceptual and structural essence of the target model of interaction.