Spanish speaking nurses are in great demand. For bilingual Hispanic undergraduate nursing students who might someday fill this need, interpersonal support can be a deciding factor in whether students successfully complete their program of study. This paper presents the results of an evaluative study of supportive relationships within a Spanish-English Nursing Education (SENE) program. A written survey was followed by individual and group interviews to reveal important sources of interpersonal support. The study showed that family members, especially spouses, played a critical role in personally supporting SENE students. Academic and motivational support, however, came from study groups and the cohort of Hispanic classmates. SENE administrators established cohorts of same year students, and encouraged the formation of study groups. Science-related college programs directed at Hispanic students could benefit from fostering and supporting program components that act to enhance interpersonal relationships.