Flexibility, creativity, and collaboration are required to successfully meet the needs of each school when scaling up family engagement programs across a diverse range of communities. Flexibility, creativity, and collaboration are required to successfully meet the needs of each school when scaling up family engagement programs across a diverse range of communities. Established in 1967 and initially implemented in Chicago, the Child-Parent Center (CPC) is a center-based early intervention that provides comprehensive educational and family-support services to economically disadvantaged families from preschool through third grade. Each CPC is located within or near an elementary school building. Receiving a federal Investing in Innovation (i3) grant in 20121 allowed further expansion of the CPC P-3 model across thirty-seven schools in four urban and suburban communities of various sizes in Illinois and Minnesota. In the work implementing the Child-Parent Center Preschool to Third Grade (CPC P-3) program, there have been a variety of barriers, along with strategies to overcome these challenges. As intervention researchers and implementers of the Midwest expansion of CPC P-3, the authors have worked with schools across diverse demographics and have identified some major barriers frequently experienced by schools, which are presented in this article.