The purpose of this article is to describe a study of the outcomes of a school-based alcohol abuse prevention initiative. The initiative was focused on identifying, developing, disseminating, and evaluating information for high school students based on the school community needs. Student learning outcomes were measured using pre- and post-tests and focus groups. Descriptive statistics were calculated for the pre- and post-tests as well as by gender. Through this study it was found that both females and males reported significant change in knowledge. Three main themes emerged from the focus groups with male students prioritizing different themes than female students. Implications for future programming keeping in mind gender differences are recommended. The method, data and findings are discussed along with implications for practice and future research.